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“This revolutionary treatment for Alzheimer’s disease uses a hyperbaric oxygen chamber, which has been shown in the past to be extremely effective in treating wounds that were slow to heal,” says Prof. Uri Ashery of TAU’s Sagol School of Neuroscience and the Faculty of Life Sciences, who led the research for the study.*
“We have now shown for the first time that hyperbaric oxygen therapy can actually improve the pathology of Alzheimer’s disease and correct behavioral deficits associated with the disease,” Prof. Ashery says, “This research is extremely exciting as it explores a new therapy that holds promise as a treatment of Alzheimer’s
Patients who undergo hyperbaric oxygen therapy for different conditions breathe in oxygen in a pressurized room or chamber. In this chamber, the air pressure is increased above that of normal air. Under these conditions, oxygen solubility in the blood increases and is transported by blood vessels throughout the body. The added oxygen stimulates the release of growth factors and stem cells, which themselves promote healing.
The TAU scientists used a mouse model of Alzheimer’s disease and built a custom-made hyperbaric oxygen chamber suitable for small animals. Then, over the course of 14 days, the team administered hyperbaric oxygen treatment to the mice for one hour per day. After 14 days, the mice underwent a series of behavioral tests as well as tissue biochemical tests to understand how hyperbaric oxygen treatment affects the pathological hallmarks associated with Alzheimer’s disease.
The treatment reduced behavioral deficiencies compared to the non-transgenic control mice, reduced plaque pathology by 40%, and reduced neuroinflammation by about 40%.
“There are serious clinical implications to this research,” says Shapira, principal investigator of the study. “Hyperbaric oxygen treatment is a well-tolerated and safe therapy used in clinics around the world for various medical conditions, including neurological disorders. Although further research is needed to elucidate the underlying beneficial mechanisms of the therapy and to evaluate its beneficial effects in various Alzheimer patient populations, it holds great potential for the treatment of Alzheimer’s disease.”
“In this hallmark study, the beneficial physiological effects of hyperbaric oxygen therapy were directly demonstrated on Alzheimer-affected brain tissue,” says Prof. Efrati. “We assume that the main challenge in human use will be to initiate the treatment at early stages before significant amount of brain tissue is lost.
*The research was conducted by PhD student Ronit Shapira of TAU’s Faculty of Life Sciences; Prof. Beka Solomon and Dan Frenkel of TAU’s Sagol School of Neuroscience and Faculty of Life Sciences; and Prof. Shai Efrati of TAU’s Sackler Faculty of Medicine, Sagol School of Neuroscience and Assaf-Harofeh Medical Center. It was published in the journal Neurobiology of Aging.
New Member Orientation at LyfeWell takes place on the second Saturday of every month and goes from 9am to 11am. There is no commitment necessary and no charge to attend.
The LyfeWell experience begins with a 45-minute orientation at a LyfeWell facility. These learning sessions equip our members with information and a “real world” view of how our modalities can help them, including an introduction to Hyperbaric Plus™.
As part of the orientation, members are given a tour of the LyfeWell facility, which allows plenty of time for interaction with key LyfeWell staff members.
We would love to give you a tour of our facility and share with you the benefits of selecting LyfeWell as your partner for better health.
Sign up to receive more information and confirm your spot at an upcoming new member orientation:
For visitors with privacy concerns, or who would simply prefer more one-on-one time with our staff and facilitators, we are happy to offer private tours that can be scheduled whenever you like, as soon as the following business day!
This consultation includes a 30-minute HBOT Plus session which allows you to get a feel for what the treatment is like. There is a $149 fee which is then applied to whichever session plan you select, which means you are essentially getting an extra HBOT+ session for free!